The brain uses up to 20% of the energy consumed by the human body, more than any other organ.  In humans, blood glucose is the main source of energy for most cells and is critical to normal function in many tissues, including the brain.


The human brain consumes about 60% of blood glucose on an empty stomach, a sedentary lifestyle. Brain metabolism is usually based on glucose in the blood as a source of energy. But during low glucose (such as fasting, endurance or limited carbohydrate intake).


The brain uses ketone bodies to fuel with less glucose demand. It can also use lactate during exercise. The brain stores glucose in the glycogen, albeit in much smaller quantities than that found in the liver or skeletal muscle. Long-chain fatty acids can not cross the blood-brain barrier, but the liver can break them down to form ketone bodies.


However, short-chain fatty acids (e.g. butyric acid, propionic acid, and acetic acid) and medium-chain fatty acids. The octanoic acid and heptanoic acid may cross the blood-brain barrier and be metabolized by brain cells.z


                                                 what is metabolism and how does it work

Although the human brain is only 2% of body weight, it receives 15% of cardiac output, 20% of total body oxygen consumption and 25% of total body glucose utilization.  The brain mainly uses glucose for energy, and depriving glucose, as it can happen in hypoglycemia, can lead to unconsciousness.


Energy consumption of the brain does not change significantly over time, but active cortical regions consume slightly more energy than inactive areas: this fact forms the basis for functional PET and fMRI brain imaging methods.  These functional imaging techniques provide a three-dimensional picture of metabolism work.



The sleep function is not fully understood; however, there is evidence that sleep increases the metabolic clearance of metabolic products, some of which are potentially neurotoxic, from the brain and can also be repairable.


Evidence suggests that increased clearance of metabolic waste during sleep occurs through increased lymphatic system function. Sleep can also affect cognitive functions, weakening unnecessary connections.



What exactly is metabolism? Let’s discuss this phenomenon

Metabolism is a physical and chemical process that takes place within every living being that helps sustain life. Metabolism helps provide energy for our basic body functions and other physical activities.


Our basic body functions such as breathing, digestion, blood circulation, cell growth, and repair require energy. Other physical activities that we do, such as walking on the road or in the park, climbing office stairs.